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Fresh vs. Frozen Embryo Transfer: What’s the Difference?

Updated: Sep 29



Throughout your fertility journey, you'll face numerous decisions, one of which may involve choosing between a fresh or frozen embryo transfer. If you're new to IVF, the differences between these two options might not be entirely clear, especially when considering the process and success rates.

Keep reading to explore how fresh and frozen embryo transfers compare, along with the advantages and disadvantages of each approach.


Fresh vs. Frozen Embryo Transfers: What’s the Difference?

Both fresh and frozen embryo transfers begin with the same steps: ovarian stimulation, monitoring, and egg retrieval. This is true whether you're doing traditional IVF or mini IVF, although the ovulation induction method varies.

After the eggs are retrieved, they are fertilized in the lab to create embryos. Here’s where the two options diverge. In a fresh embryo transfer, the embryo is implanted into the uterus within three to five days after retrieval. In contrast, a frozen embryo transfer (FET) involves freezing the embryos for implantation at a later time—whether it’s weeks, months, or even years after fertilization.


Pros and Cons of Fresh Embryo Transfer

For those eager to conceive, a fresh embryo transfer might seem like the obvious choice, as implantation happens almost immediately after retrieval. The primary benefit of this method is the potential for pregnancy shortly after the IVF process.

However, there are some drawbacks. A fresh transfer doesn’t allow time for genetic testing of the embryo. Additionally, the medications used to stimulate ovulation may interfere with the hormonal environment needed for optimal implantation, potentially affecting the uterine lining’s receptivity.


Pros and Cons of Frozen Embryo Transfer

Frozen embryo transfer is a popular option in IVF, largely because of its advantages. It allows the body time to recover from ovarian stimulation and enables the opportunity for genetic testing to ensure the healthiest embryos are chosen for transfer. This increases the likelihood of implantation success.

Frozen transfers are also ideal for individuals interested in fertility preservation, allowing them to store eggs or embryos for future use.

One potential downside is that not all embryos may survive the freezing and thawing process. However, modern advancements in technology have minimized this risk, and most embryos now successfully make it through.


Success Rates: Fresh vs. Frozen Embryo Transfers

When considering success rates between fresh and frozen transfers, the good news is that they are generally comparable. A 2020 study found no significant difference in pregnancy or live birth rates between women who underwent fresh transfers and those who chose frozen transfers.

Additionally, research suggests that maternal age may not significantly impact IVF success in fresh vs. frozen transfers, even for women over 40. However, it’s important to remember that the risk of miscarriage increases with age.


Why Nicosia Fertility?

At Nicosia Fertility, we offer customized fertility treatments tailored to each individual, increasing the chances of a successful pregnancy.

Our world-renowned fertility specialists are dedicated to supporting you at every stage of your journey. Whether you’re new to IVF or exploring different transfer options, we’re committed to helping women of all ages achieve their fertility goals.

For compassionate, personalized fertility care, Nicosia Fertility is the perfect choice. Contact us or visit our website to schedule your consultation today!

 

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