Did you know that the embryo implantation phase is one of the biggest challenges faced by specialists in reproductive medicine? This critical phase of pregnancy directly impacts the success rates of in vitro fertilisation (IVF) treatments, but there is still much to learn about it. Here’s what you need to know about this essential stage.
What Is Implantation and What Are Its Stages?
Embryo implantation is the process by which the embryo, at the blastocyst stage, attaches itself to the endometrium to continue developing. This delicate phase typically occurs between days 5 and 6 after egg fertilisation and is one of the most complex and least understood stages of pregnancy.
The process happens gradually, progressing through several stages: pre-contact, apposition, adhesion, intrusion, and invasion of the endometrial stroma.
What Are the Symptoms of Implantation?
As we’ve mentioned in previous discussions, symptoms of implantation often go unnoticed or may not appear at all. However, common signs may include nausea, fatigue, tender breasts, light implantation bleeding, or mild cramping in the belly.
What Are the Causes of Implantation Failure?
Implantation failure occurs when pregnancy is not achieved after three IVF cycles with good-quality embryos. Several factors can contribute to implantation problems, including:
Embryo Location: In cases like ectopic pregnancy, the blastocyst implants in an inappropriate area, such as the fallopian tubes, instead of the uterus.
Chronic Infections of the Endometrium: Some infections may be asymptomatic but still affect implantation. Other issues related to the uterus or endometrial receptivity can also prevent successful implantation.
Genetic Alterations: Genetic issues in the embryo, sperm, or egg can hinder implantation.
Immune System Disorders: Certain immune system conditions can cause the body to reject the embryo.
Thrombophilias: Disorders affecting blood clotting can also interfere with the implantation process.
Did you already know about this crucial stage of pregnancy? If you have more questions or concerns about implantation issues during assisted reproduction, don’t hesitate to contact Nicosia Fertility for more information!
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